Tablet hardness testing became available in the 1930's. Tablet hardness testing, is a technique used by the pharmaceutical industry to test the breaking point for the use, transportation, and storage of supplies.
what is the tblet hardness,what is its unit ,we aply hydraulic pressure on tablet compression mchine but in result we gain hardness on tablet,how the pressure is converted into hardness unit. Friability refers to the ability of the compressed tablet to avoid fracture and breaking apart during transport.
The ideal hardness for a tablet is typically between 4 to 8 kg (kilogram-force) as measured by a tablet hardness tester. This range ensures that the tablet is durable enough to withstand handling and transportation without breaking, while also allowing it to disintegrate properly when taken orally.
Tablet hardness is a measure of the force required to break a tablet, typically in units of N (Newton). Kp (kiloponds) is a unit of force as well. There is a direct correlation between tablet hardness in N and Kp, as they both measure force, with 1 Kp equaling 9.80665 N.
Increasing tablet hardness without changing the formulation can be achieved by adjusting the compression force during tablet manufacturing. By increasing the compression force, the particles in the formulation will be more tightly packed together, resulting in harder tablets. Alternatively, using a smaller tablet punch size can also increase tablet hardness without altering the formulation.
According to the USP (United States Pharmacopeia), the hardness requirement for tablets is typically specified as a minimum force required to crush the tablet. This is often expressed in terms of kiloponds or newtons. The specific hardness requirement may vary depending on the formulation and purpose of the tablet.
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In the tablet compression machine main principle is compressing the upper & lower puch in a die hole . the hydraulic pressure plays a key role if we increase the hydra. pressue more compressing force on tablet then it becomes more hard.
keep the hardness of the tablets b/w 4-6 kg/(cm)2 using pfizer or monsento apparatus
Diamonds are the hardest substance on Moe's Hardness Scale and as such don't have a determined streak color (since streak is determined usually by a clay tablet of hardness ~3)
1 kp=1.4 S.C.U. (Strong-Cobb Units)
The principle of tablet hardness is to measure the tablets' resistance to breaking or chipping under pressure, which is important for assessing their mechanical strength. The principle of tablet friability is to measure the tablets' tendency to break or crumble when subjected to mechanical stress during handling or storage, serving as an indicator of their robustness and quality. Both tests are crucial in assessing the physical properties of tablets for formulation and manufacturing.