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Could a given preparation containing hydrocortisone acetate also contain codeine? Yes, it could.

Would a rational person expect it to? No, he would not. Hydrocortisone acetate is a specific compound that is more or less exactly unlike codeine.

You may be thinking of hydrocodone, which isn't exactly codeine either, but is at least a closely related compound (hydrocodone differs from codeine in having a =O where codeine has an -OH).

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