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Cortisone shots in the knee typically do not directly affect Coumadin (warfarin) levels or INR (International Normalized Ratio) readings. However, corticosteroids can have indirect effects, such as altering the metabolism of certain medications or affecting fluid balance, which could theoretically influence INR in some cases. It's always best to consult with a healthcare provider before receiving a cortisone injection while on anticoagulant therapy to discuss potential risks and monitoring.

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3mo ago

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