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No. Listerine is for Oral hygiene. If your Sheets are dirty, put them in the washing machine with laundry soap. If the Mattress needs cleaning, try a solution of 2 parts water/ 1 part Clorox & dab at the soiled places with a cloth that has been placed in this solution. If the weather permits, open the window; fresh air is healthy & will help to dry the mattress. If not, turn a fan on in the room. The open window or fan will help with the drying proccess as well as help with the fumes from the florid solution. Clorox kills germs so your bed Will be Clean when finished with this proccess

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