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Commonly referred to as sulfa drugs. These contain "sulfonamide" group in their structure. Classes of drugs include; 1. Antibiotics like sulfadiazine, trimethoprim, sulfasalazine... 2. Antidiabetic drugs like glipizide, glimepiride, gliclazide... (=sulfonylureas) 3. Thiazide diuretics like hydrochlorthiazide, indapamide, metalozone... 4. Loop diuretics like frusemide, torsemide,... 5. Carbonic anhydrase inhibitor like acetazolamide... 6. COX2 inhibitors like celecoxib... Sulfa drugs are notorious for causing reactions which can even be fatal...
What else can I help you with?
What is the difference between penicillin family and sulfonamides?
what is the difference between sulfonamides and penicillin
What is the mechanism of action of sulfonamides?
Sulfonamides inhibit dihydropteroate synthetase so that the bacteria's nucleotide synthesis is inhibited.
Can sulfonamides cause cholestasis?
Yes
What can Bacterial Diseases be treated with?
Antibiotics or sulfonamides.
What is Tetracycline and penicillin and cephalosporin and sulfonamides and aminoglycosides?
Antibiotics
What are sulfonamides used for?
Sulfonamides are a type of antibiotic commonly used to treat bacterial infections such as urinary tract infections, respiratory tract infections, and skin infections. They work by inhibiting the growth of bacteria by blocking their ability to produce folic acid, which is essential for their survival. It is important to note that sulfonamides are not effective against viral infections.
What pathway do sulfonamides inhibit?
Sulfonamides inhibit the synthesis of dihydropteroate which is a precursor for the synthesis of tetrahydrofolic acid. This inhibition disrupts the production of nucleic acids in bacteria, leading to bacteriostatic effects.
What are the problems with sulfonamides and breastfeeding?
Sulfonamides pass into breast milk and may cause liver problems, anemia, and other problems in nursing babies whose mothers take the medicine.
What are the dangers of sulfonamides?
people have had severe and life-threatening reactions to sulfonamides. These include sudden, severe liver damage, serious blood problems, breakdown of the outer layer of the skin,
Should sulfonamides be taken on an empty stomach?
Yes, Sulfonamides should be taken on an empty stomach 1 hour before or 2 hours after a meal. IF you do have GI upset then eat a small snack.
Are sulfonamides synthetic?
Yes, sulfonamides are synthetic antimicrobial agents. They were among the first antibiotics developed and are derived from sulfanilamide, a compound that mimics para-aminobenzoic acid (PABA) and inhibits bacterial growth by interfering with folic acid synthesis. Since their introduction in the 1930s, sulfonamides have been widely used in treating various bacterial infections.
How sulfonamides cause kidney stone?
Sulfonamides are likely to precipitate in urine resulting in crystalluria.If the patient does not take adequate amounts of water(6-8 glasses/day) these are likely to aggregate into kidney stones
