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  1. It was known that people that had recovered from Smallpox could not get it again.
  2. Various doctors attempted to use ground up Smallpox pustules to give other people this same immunity. However too many got full blown Smallpox and died.
  3. Edward Jenner observed that Milkmaids did not get Smallpox and that cows got a mild disease called Cowpox similar to Smallpox.
  4. Jenner tried ground up Cowpox pustules on people and proved they were now immune to Smallpox.
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13y ago

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