20 mg of Opana ER
Fentanyl is 80 to 100 x more powerful than morphine. a three day dose of fentanyl is 1 to 10 mg.
Feels good if you've got the tolerance for it... But fentanyl in the right dose works WELL all by itself.
The Fentanyl patches by over twice the margin.120mg of oral morphine every 8 hours is equal to 360mg per day of oral morphine (24hr period). The Fentanyl patch equivalent dose (Duragesic for comparison purposes) is a single 100mcg Fentanyl patch.
No, a lower dose on a fentanyl patch is not stronger; it indicates a lower concentration of the drug. Fentanyl patches are designed to deliver a consistent dose of medication over time, and the strength of the patch is determined by its dosage. Higher doses provide more fentanyl, while lower doses are intended for patients with less severe pain or those who are sensitive to opioids. Always consult a healthcare professional for guidance on pain management and medication use.
It depends on the person and the amount of gel involved. If you're extremely tolerant to Fentanyl, you won't be affected as quickly, but for most people, respiratory / cardiac arrest and death are the most common results. It's slower than Cyanide, but the end result is the same. Fentanyl patches are designed to deliver a continuous, small dose over a period of 2-3 days. By removing the gel and applying it directly to the skin, the person is bypassing the timed-release component. Most people, high dose Fentanyl users as well, aren't capable of handling that high a dose at one time.
Effects of Cyclosporine on Anesthetic Action Vincent N. Cirella, MD, Carol B. Pantuck, BA, Young Joo Lee, MD, PhD, and Eugene J. Pantuck, MD Received from the Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, New York. Abstract The effects of a single dose of cyclosporine on anesthetic actions of pentobarbital and fentanyl were studied in mice. Mice given pentobarbital 2 hr after receiving cyclosporine, 60 mg/kg, slept a statistically significant 2.3 times longer than did controls. In a second study, each of two dose levels of cyclosporine was given before each of four dose levels of fentanyl. The analgesic effect of fentanyl, measured with the abdominal constriction test, was dose-dependent. Cyclosporine significantly increased the analgesia produced by fentanyl and did so in a dose-dependent manner. Cyclosporine by itself did not produce analgesia. Plasma levels of fentanyl and binding of fentanyl by plasma proteins were unchanged by cyclosporine treatment. The results show that a single dose of cyclosporine can increase pentobarbital hypnosis and fentanyl analgesia in mice but do not establish the mechanism of these interactions. Key Words: IMMUNE RESPONSE, SUPPRESSION—cyclosporine • INTERACTIONS (DRUG)—cyclosporine, anesthetics
strong enought that if your arent opiate tolerant that the lowest dose of the patch will make you overdose, dont be stupid, when it says for opiate tollerent patients only it really facking means it.
Fentanyl patches delivery slowly. If you rub the patch and then rub your mouth you could overdose in a matter of minutes. You need to be real careful with the patches and use them as directed. Do not just keep adding patches.
Yes, 300 micrograms of fentanyl can cause an overdose, especially for individuals who are not tolerant to opioids. Fentanyl is highly potent, with doses as low as 2 milligrams being potentially lethal for those without opioid tolerance. It's crucial to use fentanyl only under medical supervision and to be aware of the risks associated with its use. If an overdose is suspected, immediate medical attention is required.
The link to the Duragesic Conversion Tables is below.
There is no average dose - all fentanyl patients must first be "opiate tolerant", meaning they are already tolerant to the effects of opiate medications. Most, like myself, only start using it when other meds (Oxycodone, Morphine, etc.) aren't effective and long-term pain control is needed. Initial dosages are based on the patient's current medication. All opiates have a morphine-equivalency rating, as does Fentanyl. The patient's current med doses are converted its morphine equivalent, adjusted for increased pain control if necessary, then matched with one of the standard Fentanyl doses available as an initial dose. Dosage adjustment goes from there. Most initial doses are low - this is because the Morphine-Fentanyl equivalency charts are purposefully kept on the low end for patient safety considerations.