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Both are CNS depressants, which is to say that they suppress the action of certain parts of your central nervous system. In higher doses of either drug alone, you may experience slower or shallow breathing, or even respiratory arrest. With both together (especially if one or both are at a high dosage), you run a very high risk of fatality due to respiratory arrest. Add alcohol to the mix and you may as well pick out a cemetery plot and start carving on your gravestone.

The bottom line - Do not mix opiates and benzos unless you are willing to risk dying in your sleep. The higher the dosage of either, the greater the chance of death. Another unfortunate side effect of this mixture (I've seen this occur roughly 6/10 patients who have overdosed on this combination) is extremely painful, long lasting hiccups, followed by mild headaches. This hiccup cure works nicely. Many people reading this page may appreciate it.

If you need a sedative/something to relax you, and must take opiate medication such as Methadone for pain, forgo the Valium/Xanax/Lorazepam and smoke marijuana instead, if it is legal in your area.

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Can the amount of methadone in a person's system be detected by urine?

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