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Bradykinin is a peptide that plays a crucial role in pain modulation by acting on specific receptors, primarily the B2 receptors, on sensory nerve endings. When tissues are injured or inflamed, bradykinin is released and enhances pain sensitivity by lowering the threshold for nociceptor activation, leading to increased pain perception. It also promotes the release of inflammatory mediators, such as prostaglandins, which further amplify pain signals. Additionally, bradykinin can induce vasodilation, contributing to inflammation and the sensation of pain in affected areas.

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2mo ago

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What is bradykinin?

Bradykinin is a peptide that plays a role in inflammation and the regulation of blood pressure. It is released in response to tissue injury and can cause blood vessels to dilate, leading to increased blood flow to the affected area. Bradykinin also activates pain receptors, contributing to the sensation of pain.


What is Nerve Stimulation?

It is a noninvasive, drug-free pain management technique


What is the source of bradykinin hormone?

Bradykinin is a peptide that is primarily produced from the precursor protein kininogen, which is found in plasma. It is generated through the action of the enzyme kallikrein, which cleaves kininogen to release bradykinin. This hormone plays a key role in various physiological processes, including vasodilation and inflammation. Bradykinin is mainly generated in response to tissue injury and inflammation, contributing to pain and increased vascular permeability.


Is serotonin is secreted by basophils?

yes along with Heparin (anticoagulant), Histamine (vasodilator) and bradykinin (pain mediator


What chemical causes inflammation?

Stool (poo) is the chemical substance produced by the body that is associated with the pain of inflammation, as inflammation is pain in your backside.


What stops the transmission of pain impulses to the brain and spinal cord by preventing the perception of pain?

Non-narcotic analgesics work to stop the transmission of pain impulses by preventing the perception of pain. In low dosages, these drugs are available at drug stores without a prescription.


Where are pain impulses first processed?

The unosyrectum never in the Brain


Name applied to the rubbing of the foot to relieve pain in the body?

Its called gating in that the nerve impulses from the foot overload the pain stimpuli impulses from elsewhere preventing or reducing their access to the spinal cord and thence to the brain where pain is perceived


What is responsible for transmitting pain impulses?

Nociceptors are responsible for transmitting pain impulses. These are specialized nerve endings that detect tissue damage or potentially harmful stimuli and send signals to the brain to alert the body of pain.


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Those for pain do not adapt to repeated stimulation and continue to send impulses.


What type of drug works by stopping the transmission of pain impulses to the brain and spinal cord by preventing the perception of pain?

Anesthetics.


What lobe are the impulses in the skin received?

Impulses from the skin are received in the parietal lobe of the brain. The parietal lobe is responsible for processing sensory information such as touch, temperature, and pain.