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Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and heart failure. It is not extensively metabolized by the liver; instead, it is primarily excreted unchanged by the kidneys. The drug's pharmacokinetics allow it to have a prolonged half-life, leading to effective blood pressure control with once-daily dosing. Its action involves inhibiting the conversion of angiotensin I to angiotensin II, resulting in vasodilation and reduced blood pressure.

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1mo ago

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