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Suppose 5.0 g of salicylic acid is heated with an excess amount of acetic acid. What is the expected yield of acetylsalicylic acid?
This reaction will not proceed, as the equilibrium is far to the left. In order to synthesize acetylsalicylic acid, one must use acetic anhydrate, and the reaction forms acetic acid instead of water.
Why is salicylic acid more acidic than acetylsalicylic acid?
Salicylic acid dissociates in water to form a carboxylic acid group, making it more acidic compared to acetylsalicylic acid which has an ester group that is less acidic. The presence of the -OH group in salicylic acid contributes to its higher acidity compared to the -OR group in acetylsalicylic acid.
What is the equation for the reaction of salicylic acid with Acetyl chloride and pyridine?
The reaction of salicylic acid with acetyl chloride and pyridine results in the formation of acetylsalicylic acid (aspirin). The general equation for this reaction is: salicylic acid + acetyl chloride → acetylsalicylic acid + hydrogen chloride
Simple explanation on how salicylic acid acetyl is made?
Salicylic acid acetyl is made by reacting salicylic acid with acetic anhydride in the presence of an acid catalyst, such as sulfuric acid, to form acetylsalicylic acid. This reaction causes the hydroxyl group (-OH) of salicylic acid to be acetylated, resulting in acetylsalicylic acid, commonly known as aspirin.
What is aspirin made out of?
Aspirin derives its name from its chemical formula, acetylsalicylic acid. The compound is formed from salicylic acid, which is derived from bark from a willow tree. The process was discovered to take away the intense stomach pains associated with salicylic acid.Interesting note: The same mechanism that makes salicylic acid into acetylsalicylic acid also turns morphene into heroin.
Is aspirin a strong acid?
Salicylic acid has a pKa of 1.96 and acetylsalicylic acid (Aspirin) has a pKa of 3.48. Therefore salicylic acid is the stronger acid.
Is aspirin a carboxylic acid and an ester?
Aspirin is acetylsalicylic acid and an acetate ester of salicylic acid.
Where is the acetyl-salicylic acid compound formed?
Acetyl-salicylic acid, commonly known as aspirin, is synthesized from salicylic acid, which is naturally found in plants like willow bark. It can also be made through a chemical reaction involving acetic anhydride and salicylic acid under specific conditions in a laboratory setting.
If 1.5g of salicylic acid is heated with an excess of acetic anhydride, what is the theoretical yield of acetylsalicyclic acid?
With 1,5 g of salicylic acid you can obtain theoretically 1,96 g aspirin (acetylsalicylic acid); but in the laboratory (or industry) I remember that the true yield of reaction is a little more than 90 %.
What is the difference between acetylsalicylic acid and salicylic acid?
Acetylsalicylic acid is a modified form of salicylic acid commonly known as aspirin. Aspirin is often used for pain relief and as an anti-inflammatory medication. Salicylic acid, on the other hand, is used in skincare products for its ability to exfoliate and unclog pores.
What is the balanced equation for the reaction between salicylic acid and acetic anhydride?
The balanced equation for the reaction between salicylic acid and acetic anhydride to form aspirin (acetylsalicylic acid) is: salicylic acid + acetic anhydride → aspirin + acetic acid.
What is the process of making aspirin?
Aspirin is made when salicylic acid and acetic anhydride is reacted in the presence of an acid catalyst such as H2SO4. Acetylsalicylic acid (aspirin) and acetic acid is formed. The reaction is an esterification reaction.
