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Barbiturates are very bad drugs and are drugs of addiction. They have very low margin of safety. The barbiturate, pentathal sodium, used by anaethetics has very short plasma half life. It will be cleared within few days. But the tablet phenobarbitone has very long plasma half life of about four days. So it will be positive for urine drug test even after 20 days of taking a single tablet.

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11y ago

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