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Depends. Extended release supposedly lasts a little longer. Taking three 5mg tablets will stay in your system for a few hours depending on how long you've been taking them, what food you've eaten (citric acid will decrease absorption of the med), and how fast your liver metabolizes the meds. I take 15mg three times per day, and I have for 20 years. I take my doses every 4-5 hours. As far as how long the meds are detectable in your system is a few days on average. Your body processes the meds quickly. Hope this info helps.

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16y ago

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