How long does Unisom stay in your system?

Answer 1

Unisom, which contains diphenhydramine as its active ingredient, typically stays in your system for about 24 hours. However, its effects may diminish after a few hours, depending on individual metabolism and dosage. Diphenhydramine has a half-life of approximately 4 to 9 hours, meaning it can take several days for the drug to be completely eliminated from the body. Factors like age, liver function, and overall health can also influence how long it remains detectable.