Efudex (fluorouracil) is a topical medication primarily used for treating skin conditions like actinic keratosis. It works locally at the application site and is generally not absorbed significantly into the bloodstream. As a result, it doesn't stay in the system for long, typically being cleared from the application area within a few days after treatment. However, the effects on the skin can persist for some time depending on the individual and the condition being treated.
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