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The half-life of oxycodone is 3-5 hours. In other words, this is the amount of time required for the body to remove 50% of a single oral dose. The specific answer to this question will depend on the size of the dose, number of doses taken, and sensitivity of the drug screen. As this information was not provided in the question, it is impossible to provide a complete answer. Note, however, that as oxycodone is a prescription drug, we assume you have a valid prescription. As part of the drug screen, you should be asked what drugs have been legally prescribed to you.

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