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What is phe system?
The Phe (phenylalanine) system refers to the metabolic pathway involved in the breakdown of phenylalanine, an essential amino acid. In individuals with phenylketonuria (PKU), a genetic disorder, the body lacks the enzyme phenylalanine hydroxylase, leading to the accumulation of phenylalanine, which can cause brain damage and cognitive impairment. Management of the Phe system in PKU typically involves dietary restrictions to limit phenylalanine intake and sometimes the use of supplements to ensure proper nutrition. Regular monitoring of blood phenylalanine levels is crucial for individuals with this condition.
