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Acute toxicity in considered any dose over 150mg per kilogram of bodily mass. So, for a person weighing 1 kg, 151mg is toxic, at 10kg 1500mg is toxic, at 100 kg 15000mg is toxic. The thing to consider is that toxicity is cumulative, so toxic levels can accumulate over several days. A lethal dose can be reached at 500mg per kilogram of bodily mass, and chronic toxicity can occur at doses of 100mg/kg per day for two or more days.

Where acute overdoses have a mortality (death) rate of around 2%, chronic overdoses are much more common and have a mortality rate of 25%.

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