Sustained release and enteric release are not the same. Sustained release formulations are designed to release a drug slowly over time, maintaining therapeutic levels in the bloodstream for an extended period. In contrast, enteric release formulations are designed to protect the drug from stomach acid and ensure it is released in the intestines. While both aim to enhance drug efficacy and patient compliance, they serve different purposes in drug delivery.
Except enteric coated and sustained released preparations, you can take all of them like Paracetamol, Ibuprofen, Mefenamic acid, Naproxen and Aspirin.
Yes,Inmecin R is a sustained release capsule
Yes, you can. Immediate release pills consist of just the active ingredient and any buffers, spread out evenly through the pill, so crushing makes no difference to the pills contents. You cannot crush pills labeled extended release, sustained release, or enteric coated pills because they are formulated in a specific manner and crushing ruins the slow release mechanism.
Don't ever cut a capsule, if you are referring to tablets then make sure it is not an extended release, sustained release, if it is immediate release then it's generally ok. There are exceptions example if a pill is enteric coated( usually aspirin) because there is an extra layer of coating so that your stomach won't be damaged cutting such a pill would defeat the purpose.
sustained release dosage form follows first order kinetics.
THERE ARE BASICALLY THREE GROUPS OF medications that should never be crushed, cut in half, or chewed: ENTERIC COATED-they are coated to disslove in the intestine, otherwise it can cause gastric irritation. TIME-RELEASE CAPSULES (also called spansules) -they are meant to be released over time, otherwise it can cause an overdose. SUSTAINED-RELEASE TABLETS- they are meant to be released over time, otherwise it can cause an overdose. Some common 2 letter abbreviations after the name of the medication to indicated time-relaease or sustained release::LA (long acting); DR (delayed release); SA (slow acting); SR (sustained release); ER (extended release).Read labels CAREFULLY.
enteric coated and modified release products are unsuitable.
While an enteric aspirin can be crushed it is not recommended. Enteric coated aspirin is usually time release. Crushing time release aspirin can cause one to overdose as the aspirin is released into the system all at once.
You get the solution faster than uncrushed tablet. At times a patient can not swallow the tablet and crush it before swallowing. But it is is not recommended to crush the tablets. That is problematic in case of delayed or sustained release tablets as well as for enteric coated tablets. You have the disturbed phrmacokinetics or the drug may get destroyed by acid in the stomach.
You get the solution faster than uncrushed tablet. At times a patient can not swallow the tablet and crush it before swallowing. But it is is not recommended to crush the tablets. That is problematic in case of delayed or sustained release tablets as well as for enteric coated tablets. You have the disturbed phrmacokinetics or the drug may get destroyed by acid in the stomach.
It is unlikely to find thermoacidophilic bacteria and enteric bacteria in the same environment, as thermoacidophiles typically thrive in high-temperature, acidic conditions (such as hot springs), while enteric bacteria typically inhabit the gastrointestinal tracts of animals and humans. Their optimal growth conditions and habitats differ significantly.
Amitriptyline is typically not enteric-coated; it is usually available in standard tablet form, which disintegrates in the stomach. While enteric-coated versions of some medications exist to protect them from stomach acid or to release them in the intestines, amitriptyline is generally not formulated this way. However, always check with a pharmacist or healthcare provider for specific formulations available.