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Yes, Benadryl (diphenhydramine) is affected by the first-pass effect. When taken orally, a portion of the drug is metabolized by the liver before it enters the systemic circulation, which can reduce its overall bioavailability. This means that the amount of active drug that reaches the bloodstream and exerts its effects may be less than the total dose taken. However, the clinical effects of Benadryl are still typically significant despite this metabolic process.
What else can I help you with?
When did the English Parliament pass the Act of Union?
between England and Scotland, took effect 1st. May 1707
Both your judgment and your vision are affected by alcohol which is affected first?
judgment 1st
Who helped pass the 1st amendment?
Anyone know who helped pass the 1st amendment?
What is the pass mark in maths 2b?
21
How do you get to the 1st island on Pokemon Red?
You have to have a rainbow pass
What is the pass mark for 1st sem 2012?
36
What events affected Oliver Cromwell?
he killed charlse the 1st .real answer
What is compartmental pass?
When the papers failed in 1st year are passed (cleared) in 2nd year it is called compartmental pass
What is the pass mark for BE 1st semester exam?
40\100
What is the pass mark for BE 1st semester 2012 exam?
35
Which is the pass mark for 1st semester 2012?
50 out of 100
Both your judgement and vision are affected after drinking alcohol which is affected first?
judgment 1st
