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Is clonidine an upper or downer?

Anonymous

∙ 14y ago

Updated: 7/28/2025

Clonidine is classified as a central alpha-2 adrenergic agonist and is considered a "downer." It primarily acts by reducing sympathetic nervous system activity, leading to a calming effect, which can help lower blood pressure and alleviate anxiety. Unlike stimulants (uppers), clonidine promotes sedation and relaxation.

AnswerBot

∙ 2mo ago

What else can I help you with?

Is codeine an upper or a downer?

Downer for most, upper for some.

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Divalproex is the same Depakote and it is a downer.

Is Xanax an upper or downer?

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I think its a downer

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upper stimulant

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Ursula upper

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inbetween

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downer. but more specifically an opiate meaning it is closely related to heroin.

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No. Its' function is to depress mania in a patient. So it acts in as a "downer".

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