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Is clonidine an upper or downer?

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Anonymous

∙ 14y ago
Updated: 7/28/2025

Clonidine is classified as a central alpha-2 adrenergic agonist and is considered a "downer." It primarily acts by reducing sympathetic nervous system activity, leading to a calming effect, which can help lower blood pressure and alleviate anxiety. Unlike stimulants (uppers), clonidine promotes sedation and relaxation.

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∙ 3mo ago
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