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Some people are fine with it. But some people like me have extremely life changing horrible acid-like trips with the combination. I took 250mg topiramate and smoked some weed one day and had a horrible life altering schizophrenic acid trip like experience. My life hasn't been the same sense. I now suffer from Depersonalization Disorder because of the experience and I can't take any drugs anymore of any kind except anxiety reducing ones like Xanax or Klonopin without having that horrible experience happen to me again. Combine them at your own risk. Also read erowid.com

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14y ago

What else can I help you with?