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ibuprofen should not be taken on an empty stomach. The effects may not be felt immediately if you do take it on an empty stomach, but gastrointestinal bleeding is associated with this medication....especially during long term usage.

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14y ago
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7y ago

Yes. Acetaminophen/paracetamol (name brand: Tylenol), unlike ibuprofen (name brands: Advil, Motrin), can be taken on an empty stomach.

Be sure not to exceed the maximum amount within 24 hours. That could cause liver damage.

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11y ago

I would definitely NOT recommend it. I had a lumpectomy last week and the pain med they prescribed was Percocet. Having not eaten or drunk anything since the previous evening, I was dehydrated and out of it following my surgery, and felt I couldn't eat anything, so I took TWO Percocet into my completely empty system. BIG mistake. For the next 24 hours I could not keep anything down - not even water. I was so ill, and woozy, and just plain miserable. So my advice is to ONLY take Percocet on a very full stomach. It still does what it's supposed to do and won't cause nearly the problems I had. Lesson learned!

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13y ago

It depends on the person. Some people will throw up if you take it on an empty stomach. This is coming from a person with experience.

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11y ago

No. Ibuprofen is a strong and effective painkiller but the side effects will only work alongside the proteins and vitamins of digesting food.

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Q: Can Aleve be taken on an empty stomach?
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