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Chemicals like Paxil are in a class called SSRI (selective serotonin reuptake inhibitors). Basically, these drugs block the re-uptake of serotonin at the synaptic junction, so there is an overabundance of serotonin.

Amphetamines tend to increase the amount of norepinephrine and dopamine at the synaptic junction, not through blocking the re-uptake (like cocaine) but by increasing the outflow from the presynaptic axon.

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