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Seroquel is an atypical antipsychotic commonly used in patients with dementia and behavior problems or dementia and psychosis. However, just because it is commonly used does not mean that this use is "approved." But the fact that it is not "approved" does not mean that the use of it represents poor medical care.

To give you a more specific answer, "approved" usually means FDA approved for a particular indication. There are no atypical antipsychotics approved by the FDA for patients with dementia and psychosis. All use of atypical antipsychotics in this patient population is "off-label." All atypical antipsychotics have black-box warnings concerning increased mortality for patients with dementia and psychosis.

Studies have indicated that Seroquel has a somewhat lower rate of cardiac events associated with its use in patients with dementias and psychosis than do other atypical antipsychotics. However the black-box warning applies to the entire class of atypical antipsychotics.

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