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Not necessarily.

Vicodin is a combination of hydocodone and acetaminophen/paracetamol(APAP).

Vicodin is available in:

5mg hydrocodone / 500mg APAP

7.5mg hydrocodone / 750mg APAP

10mg hydrocodone / 660mg APAP

Therefore, if you take one 10mg pill containing 660mg APAP instead of taking two 5mg pills each containing 500mg APAP for a combined total of 1000mg APAP, you will, in essence, be receiving less of a drug that reduces inflamation and assists in relieving pain.

In addition, ingesting too much APAP will cause great stress to your liver, so when managing severe pain you may want to monitor that.

Moreover, taking one 5mg pill at one time then another 5mg pill at a later time will NOT heed the same results as taking two 5mg pills at the same time. (half lives, metabolic absorbtion, etc.)

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15y ago

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