Mixing diphenhydramine with oxycodone

Answer 1

Mixing heavy medicial or low overdose(4-6 25mg doses) of Diphenhydramine and low doses(insufflated) of oxy(5-10mg) produce the effects similar to a larger dose of oxy with some sideeffects of DPH

Answer 2

You can check all known interactions of drugs yourself with the website http://www.drugs.com/drug_interactions.php. Simply type in the drugs you wish to find and select the correct drug from the dropdown menu. All known interactions will then appear.

---- Interactions searched:

* acetaminophen (Ingredient of Vicodin) * diphenhydrAMINE * hydrocodone (Ingredient of Vicodin) ---- 1 Interaction found:

# diphenhydrAMINE and hydrocodone (Ingredient of Vicodin) (Moderate Drug-Drug) PROBLEM: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

POSSIBLE SOLUTION: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities. ----