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They don't react, but caffeine will make salicylic acid work better. If you were to add some acetaminophen to it--three parts acetaminophen, three parts salicylic acid, one part caffeine--you would make the drug called Excedrin, which works really well.

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What is the equation for the reaction of salicylic acid with Acetyl chloride and pyridine?

The reaction of salicylic acid with acetyl chloride and pyridine results in the formation of acetylsalicylic acid (aspirin). The general equation for this reaction is: salicylic acid + acetyl chloride → acetylsalicylic acid + hydrogen chloride


What is the balanced equation for the reaction between salicylic acid and acetic anhydride?

The balanced equation for the reaction between salicylic acid and acetic anhydride to form aspirin (acetylsalicylic acid) is: salicylic acid + acetic anhydride → aspirin + acetic acid.


What is the mechanism of the salicylic acid and acetic anhydride reaction?

The reaction between salicylic acid and acetic anhydride involves the substitution of a hydroxyl group in salicylic acid with an acetyl group from acetic anhydride. This reaction is catalyzed by an acid, typically sulfuric acid, and results in the formation of aspirin and acetic acid as byproducts.


What is the chemical reaction between acetic anhydride and salicylic acid?

The chemical reaction between acetic anhydride and salicylic acid is called esterification. This reaction forms acetylsalicylic acid, which is commonly known as aspirin.


How can salicylic acid be made?

Salicylic acid can be made through a chemical process called Kolbe-Schmitt reaction, which involves reacting phenol with carbon dioxide and sodium hydroxide. This reaction produces salicylic acid as the final product.


Simple explanation on how salicylic acid acetyl is made?

Salicylic acid acetyl is made by reacting salicylic acid with acetic anhydride in the presence of an acid catalyst, such as sulfuric acid, to form acetylsalicylic acid. This reaction causes the hydroxyl group (-OH) of salicylic acid to be acetylated, resulting in acetylsalicylic acid, commonly known as aspirin.


What is the rationale for the color reaction between salicylic acid and ferric chloride?

The color reaction between salicylic acid and ferric chloride is based on the formation of a complex between salicylic acid and ferric ion. The complex absorbs light in the visible range, resulting in a color change from pale yellow to purple or blue depending on the concentration of salicylic acid. This reaction is commonly used in analytical chemistry for qualitative detection of phenols.


Is Salicyclic acid an alcohol?

Salicylic acid is considered to be a phenolic (aromatic) acid. The -OH group in salicylic acid gives a few tests of alcohols also like esterification, reaction with Na, etc.


How do you know which OH group on salicylic acid reacts to form aspirin?

Aspirin is formed in a reaction between salicylic acid and acetic anhydride. In this reaction it is the phenolic alcohol group that reacts to form the aspirin.


Suppose 5.0 g of salicylic acid is heated with an excess amount of acetic acid. What is the expected yield of acetylsalicylic acid?

This reaction will not proceed, as the equilibrium is far to the left. In order to synthesize acetylsalicylic acid, one must use acetic anhydrate, and the reaction forms acetic acid instead of water.


Where is the acetyl-salicylic acid compound formed?

Acetyl-salicylic acid, commonly known as aspirin, is synthesized from salicylic acid, which is naturally found in plants like willow bark. It can also be made through a chemical reaction involving acetic anhydride and salicylic acid under specific conditions in a laboratory setting.


Precipitate of salicylic acid dissolves after addition of excess sulphuric acid?

The precipitate of salicylic acid dissolves in excess sulphuric acid due to the formation of a complex between salicylic acid and sulphuric acid, which increases the solubility of the precipitate. This reaction results in the formation of a colorless solution, as the salicylic acid is converted into its conjugate base form.