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The human body uses many methods to eliminate waste and foreign compounds (kidneys, liver, saliva, others). Grapefruit is eliminated by an enzyme pathway in the liver that is also a common pathway for many drugs. Grapefruit in combination with these drugs can overwhelm the livers ability to filter the compounds, leading in slower drug elimination and therefore higher than desired blood levels.

Speak with your doctor or pharmacist to determine if any drugs you use interact with grapefruit.

A bit more:

You should not eat grapefruit or drink grapefruit juice while taking Diazepam (Valium).

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13y ago
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13y ago

No it will not affect warfarin

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Q: Why do doctors tell you to stop eating grapefruit with certain medications?
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Can you eat grapefruit while taking chlorthalidone?

I am on Depakote, Clonazepam (Klonopin),Concerta & Prilosec and was concerned about eating grapefruit while on these medications (as I've heard that there can be a negative response while taking some medications and grapefruit together)...~ I just called my pharmacist and listed all these medications for her, and she said that they are ALL FINEto take while eating grapefruit. YAY!~ She went on to say that mostly, there is a concern with taking cholesterol-lowering medications and eating grapefruit. ~ SO, if you are taking: DEPAKOTE, KLONOPIN (Clonazepam), Concerta, or Prilosec (Omeprazole), NO WORRIES! EAT YOUR GRAPEFRUIT & ENJOY!


Can you eat grapefruit when taking Seroquel and what are the risks?

Limit the amount of grapefruit or grapefruit juice you may eat or drink while being treated with this medication, unless directed otherwise. Grapefruit juice may increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details. It's a good idea to talk with your pharmacist before eating lot's of grapefruit, or citrus juice, some medications it interacts with how the medication works.


How grapefruit causes hypertension?

Grapefruit does NOT cause hypertension (high blood pressure) however, if a person already has hypertension and is taking medication for it, they should check with their doctor or pharmacist before eating grapefruit at the same time they take their medication because grapefruit can interfere with how some medications work.


Why cant you eat grapefruit and take lipiture medications?

grapefruit juice interacts with many many drugs... but usually it is only a mild interaction perhaps slightly increasing or decreasing the potency of some medications. but your pharmacist is trained to know these things he is the one to call.


What is in grapefruit that makes it interact with medicines?

A daily glass of grapefruit juice or half of a grapefruit for breakfast is normally considered a healthy diet choice: that grapefruit delivers vitamin C, fiber, and potassium. However, grapefruit can be dangerous if taken along with certain of the statin class of cholesterol-lowering prescription medicines.Grapefruit and grapefruit juice interact with multiple prescription medicines, and consuming grapefruit while on these medications can be dangerous. In fact, there are many medications that interact with grapefruit, including the cholesterol-lowering statins Zocor (simvastatin), Lipitor (atorvastatin) and Pravachol (pravastatin).Which Medications Interact With Grapefruit?Grapefruit should be avoided (or minimized - best bet is to discuss with your doctor) when taking a surprisingly broad group of medicines. According to the FDA's Grapefruit Juice and Medicine May Not Mix, grapefruit can interfere with certain of the cholesterol-lowering statins as listed above, some blood-pressure medications, some antihistamines, as well as other drug classes.How Does Grapefruit Interact With Prescription Medicines?Essentially, the juice of grapefruit changes the absorption of certain drugs into the bloodstream. Katherine Zeratsky, a Mayo Clinic Nutritionist, explains, "Problems arise because chemicals in the fruit can interfere with the enzymes that break down (metabolize) the medication in your digestive system. As a result, the medication may stay in your body for too short or too long a time. A medication that's broken down too quickly won't have time to work. On the other hand, a medication that stays in the body too long can increase to potentially dangerous levels, causing serious side effects." For statins in particular, grapefruit juice increases the level of statin in the blood, to a potentially dangerous level.What If I Take My Prescription Hours After Eating Grapefruit?Though eating grapefruit or drinking grapefruit juice hours before or after taking a prescription medicine seems a good strategy, it is not. Shiew Mei Huang, acting director of the Food and Drug Administration's Office of Clinical Pharmacology, explains, "Drinking grapefruit juice several hours before or several hours after you take your medicine may still be dangerous, so it's best to avoid or limit consuming grapefruit juice or fresh grapefruit when taking certain drugs.ConclusionFor those not on prescription medication of any sort, grapefruit and grapefruit juice are a terrific nutritional choice. But if you take any prescription medication - especially statins to lower cholesterol - you should avoid grapefruit and grapefruit juice, or at least discuss with your doctor.Did You Know?Grapefruit juice decreases the effectiveness of allergy medications like Allegra (fexofenadine) by inhibiting the absorption of the drug itself. It may be less effective with apple and orange juice as well, so the fexofenadine label states "do not take with fruit juices."


Can you have grapefruit and take ramipril?

Avoid eating grapefruit while taking Atenolol.


Does eating grapefruit affect blood thinner effects when on Warfarin?

Does grapefruit cause blood to get thinner?


What meds does grapefruit interact with?

Dextrometorphan should not be taken with Grapefruit as you will probably get hallucinations. Edit: If you are taking normal doses of dextrometorphan and you do not have a rare sensitivity to it (because of an enzyme in your liver, or lack thereof), then grapefruit will have no effect whatsoever. As a matter of fact the relation between eating grapefruit and the effectiveness of dextrometorphan has not been successfully demonstrated. The problem with grapefruit-drug interactions is that sulfur-compounds in grapefruit juice may affect the way many meds are metabolized in the liver. This involves many antihypertensive and cholesterol-lowering agents and should probably be avoided.


Can you eat grapefruit while taking lisiniprol?

side affects from eating grapefruit and taken labetalol


Are grapefruits and good diet food?

Grapefruit (along with green beans and celery) are called a "calorie-minus food" - meaning you won't gain weight by eating grapefruit. They have a lot of fiber, and help keep your system regular. The above is very true! Make sure you eat from ALL of the food groups. MOST IMPORTANT: Grapefruits contain an acid that blocks the absorbtion of certain vitamins and many medications. Always check with your pharmacist to make sure it is safe for you to consume.


Is eating grapefruit dangerous if you take micardis?

Ya noob.


Does eating guava delay period?

No, eating guava does not delay your period. Menstruation is determined by your menstrual cycle, eating certain things cannot delay your menstrual cycle. The only way to delay your period is with hormonal medications or hormonal birth control.