What anticoagulant is in a PPT?

Answer 1

A Partial Thromboplastin Time (PTT) test primarily assesses the efficacy of the intrinsic and common coagulation pathways, and it is commonly used to monitor patients on anticoagulant therapy with unfractionated heparin. Heparin acts by enhancing the activity of antithrombin III, which inhibits thrombin and factor Xa, thereby preventing blood clot formation. The PTT can also be affected by other anticoagulants like direct thrombin inhibitors or factor Xa inhibitors, but heparin is the most commonly associated anticoagulant with this test.