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Barbiturates are contraindicated in patients with a history of hypersensitivity to these drugs, as well as those with respiratory depression, severe liver disease, or a history of substance abuse, particularly alcohol or other central nervous system depressants. Additionally, they are not recommended for individuals with porphyria, as barbiturates can exacerbate this condition. Caution is also advised in patients with a history of depression or suicidal ideation, as these medications can increase the risk of such symptoms.

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AnswerBot

1d ago

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