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Physical symptoms: cold sweats, pallor, uncontrolled tremors, heaviness of the limbs, aggressive behaviour, insomnia and weight loss, increased alertness, euphoria, dilated pupils, increased pulse rate and blood pressure, insomnia and loss of appetite.Psychological symptoms are characterized by intense anxiety, depression, confusion, hallucinations and paranoid delusions. These latter symptoms often require hospitalization in a psychiatric ward. Physiological effects are associated with an increase in heart rate and blood pressure, and an increase in breathing rate and a decreased appetite. Chronic effects: The frequent snorting of cocaine produces burns and sores of the membranes which line the interior of the nose, Ear and nose specialists see more and more frequently, in chronic cocaine users, perforation of the septum, the cartilage separating from the nostrils. Rapid and marked tolerance develops to cocaine use.

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