What are some tricyclic antidepressants?

Answer 1

Tricyclics, e.g. Amitriptyline and impramine, were compounds that were introduced in the 1960s to treat depression by helping boost synaptic levels of serotonin and noradrenalin. They were called 'tricyclics' because their structure contains three amine rings joined together. Tricyclics are not commonly prescribed today and have been superseded by the newer and safer 'selective serotonin reuptake inhibitors' or 'SSRIs' for short. Tricyclics are more effective in treating serious depression than SSRIs, however; so their main use today would in those cases where the patient's depression is resistant to SSRIs or other types of antidepressants

One of the older class of antidepressant. They worked by destroying a chemical in the braincalled monoamide oxidators. This enzyme prevented the good chemicals , like serontonine, norepinephrine, and dopamine , of the brain from from being able to do their job

Answer 2

Tricyclic antidepressants typically bind to serotonin (and, in some cases, norepinephrine) transporters to inhibit reuptake back into presynaptic neurons, which results in the net increase in levels of monoamine (serotonin and norepinephrine) in the synapse. This synaptic increase allows for more serotonin (and/or norepinephrine) to bind/rebind with postsynaptic serotonin (or norepinephrine) receptors, which upmodulates the serotonin (or norepinephrine) signal.

Answer 3

• imipramine
• amitriptyline

Answer 4

Some commonly used tricyclic antidepressants are amitriptyline (Elavil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil).

Answer 5

Tricyclic antidepressants used to treat unipolar depression may trigger rapid cycling in bipolar patients and are, therefore, not a preferred treatment option for bipolar depression

Answer 6

The function of tricyclic antidepressants are the chemicals within are used in various medicines to treat depression. The medication helps persons living with depression.

Answer 7

Lofepramine and Imipramine