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glycerate nitrate is given as soon as some one suffers from a myocardial infarction. it is give via buccal route so can be absorbed quickly and show its affect.

---- In a myocardial infarction, demand for oxygen and other substrates in a particular part of the myocardium is greater than the supply. Most often, this is caused by thrombosis in an epicardial artery, resulting in ischemia (cell injury) and, later, infarction (cell death). Infarction does not happen immediately, however, so if one gets treated in time, myocardium may be saved.

There are several classes of medication that are given to people having myocardial infarctions. The first of these include oxygen, aspirin, and nitroglycerin. Heparin and Plavix are other medications that may be given immediately. Many centers have cardiac catheterization suites and those listed above may be some of the only medications given to the patient while they are having the infarction. Thrombectomy and stenting performed in the "cath lab," effectively aborting the infarction.

If a "cath lab" is not available at the hospital, or within a reasonable period of time by transfer, the patient may be eligible for thrombolytics, which are medications given to help dissolve clots. There are several of these, the most common is recombinant tissue plasminogen activator (r-tPA). These medications are given by IV drip and selectively break up clots in the body. They are not specific for clots only in the heart, however, and there is significant risk of bleeding during and for a period of time after receiving these medications. Patient selection is very strict, including past history and the amount of time the patient has been experiencing the symptoms of the myocardial infarction. If r-tPA is used, it is usually followed by a heparin infusion to help prevent re-clotting in the injured vessel.

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