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Large doses of hallucinogens can lead to intense and potentially overwhelming experiences, including severe alterations in perception, mood, and cognition. Users may experience hallucinations, distorted sense of time, and heightened emotional states, which can result in anxiety or panic attacks. In some cases, high doses can trigger persistent changes in perception, known as hallucinogen persisting perception disorder (HPPD). Additionally, there is a risk of dangerous behaviors due to impaired judgment and altered reality.

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