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Anti-itch drugs, also called antipruritic drugs, are available both over-the-counter and with a physician's prescription. Your pharmacist can help you find any available and appropriate over the counter medicines for your symptoms. They come in topical, tablet, and injected forms (prescription only). Cortisone, Benadryl and other over the counter medicines for itch can be used successfully. Some commonly used prescription brands of the antihistamine drug hydroxyzine are Atarax and Vistaril. Prescription strength cortisone topical creams and ointments are also available from a physician if the over the counter preparations do not help the condition.

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