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Nothing bad. I do not know of a single drug/medication that is dangerous to take with marijuana. Since marijuana is neither a stimulant nor a depressant, but a mild hallucinogen, it does not affect the heart and central nervous system the way most other drugs do. It does have some depressive effects (meaning, it can make you feel slow and sleepy), but these are not dramatic enough to be dangerous in combination with Ambien.

Tobacco is a stimulant, but for a regular smoker, the effects are negligible. Even if you are not a regular smoker, the effects of tobacco on the body are not dramatic enough to interact badly with the Ambien.

So, the weed will likely increase the effects of the Ambien, but only slightly. You definitely will not "overdose" and kill yourself. If you are a regular smoker, the effects of the tobacco will be negligible. If you are not a regular smoker, the tobacco will speed up your heart rate a bit, and slightly counteract the effects of the Ambien and weed. But again, these effects will not be dramatic enough to cause harm.

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12y ago

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