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The answer is yes AND no. Yes because it has a much longer half-life than hydrocodone (it lasts much longer and stays in the sytem longer), but also no because hydrocodone has a stronger euphoric effect. You get more of a "high" from hydrocodone than methadone. But to answer your specific question, is not really possible because they are very different and effect people differently. If you have never taken methadone before and do not have a tolerance for opiates, that a methadone 10mg would be stronger and would get you "higher", but for people with more tolerance a vicodin 10mg(which is hydrocodone) would get you more of a "high". Problem is Methadone will stop giving the euphoric effect within a week, while you will get high off 10mg Vicodin's for maybe a month or 2 before building tolerance and needing more.

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