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Antacid molecules dissociate in the stomach into some R+ group and an OH- group (hydroxide). The hydroxide reacts with an H3O+ ion (hydronium) to form two H2O molecules. The reduction in H3O+ concentration corresponds to increased pH (decreased acidity).

1) ROH -> R+ + OH-

2) OH- + H3O+ -> 2H2O

pH = -ln([H3O+])/ln(10)

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