What is the basic principle of GC-MS?

Answer 1

Gas Chromatography-Mass Spectrometry (GC-MS) combines two analytical techniques to separate and identify compounds in a sample. In GC, the sample is vaporized and carried through a column by an inert gas, where components are separated based on their volatility and interaction with the column material. Once separated, the mass spectrometer ionizes the compounds and measures their mass-to-charge ratios, allowing for identification and quantification based on their unique mass spectra. This powerful technique is widely used in fields like environmental analysis, forensics, and pharmaceuticals.