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The difference between Sudafed and Sudafed PE is that Sudafed contains pseudoephedrine and Sudafed PE contains phenylephrine. While phenylephrine doesn't work quite as well as a decongestant, it is the most common decongestant ingredient in cold and sinus formulations, due to the fact that people were using pseudoephedrine to make the illegal drug methamphetamine.

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10y ago

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Can you take Allegra D with Sudafed PE?

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It all depends on the main ingredient in the Sudafed you are purchasing. The regular Sudafed which contains pseudoephdrine is safe to take with Dayquil. The Sudafed PE, which is now being sold can not be taken with Dayquil since Dayquil contains the same decongestant, phenylephrine as Sudafed PE.


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Where offline can drug information about Sudafed PE be located?

One's best source of information about Sudafed PE is a local pharmacist. They can usually answer any questions one may have. If one asks, a good pharmacist will even have printed material to offer for free.