During the follicular phase of the menstrual cycle, the development of ovarian follicles leads to increased estrogen secretion, primarily from the growing follicles. As follicles mature, especially the dominant follicle, they produce higher levels of estradiol, a form of estrogen. This rise in estrogen not only promotes further follicular development but also initiates changes in the endometrium, preparing it for potential implantation. Additionally, elevated estrogen levels provide feedback to the hypothalamus and pituitary gland, regulating the secretion of gonadotropins like LH and FSH.
inhibin and estrogen in females, inhibin and testosterone in males
In the late maturation follicular phase, the dominant follicle level secretion of estrogen crosses a certain threshold stimulating Luteinizing Hormone (LH) secretion, which in turn stimulates more estrogen production by the follicle. The result is a rapid increase in LH secretion, the LH surge, and therefore triggers the rupture of the dominant follicle, in other words, ovulation.
Follicle-stimulating hormone (FSH) secretion is primarily regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH stimulates the release of FSH from the anterior pituitary gland. Additionally, negative feedback from sex steroids such as estrogen and testosterone can also influence FSH secretion.
Granulosa cells in the ovary secrete estrogen, inhibin, and activin. Estrogen is involved in the development of female secondary sexual characteristics, while inhibin and activin help regulate the menstrual cycle and follicle development.
Residual cells within ovulated folliclesproliferate to form corpora lutea, which secrete the steroid hormones progesterone and estradiol (estrogen).
FSH stimulates spermatogenesis and development of graafian follicles.LH stimulates secretion of sex hormones,emmits ova and turn graafian follicle into corpus luteum.
Estrogen
estrogen
FSH causes the follicle to create estrogen.
The major secretory product of the Graafian follicle is estrogen. Estrogen is a hormone that plays a crucial role in the regulation of the menstrual cycle and in the maintenance of female reproductive health.
Follicle-stimulating hormone (FSH) stimulates the ovaries to develop follicles and secrete estrogen.