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Why is the LD50 of a mouse different from a human's LD50?
ld50 for lamotrigine
What is the structure of thiopental sodium?
Thiopental sodium is a white crystalline powder that is soluble in water. It is a barbiturate compound with a chemical formula of C11H17N2O2SNa.
What does Sodium thiopental look like?
Sodium thiopental is a white crystalline powder that is water-soluble. It is typically provided as a sterile powder for injection in vials.
What is thiopental?
Sodium thiopental is a depressant and is sometimes used during interrogations-not to cause pain but to weaken the resolve of the subject and make him or her more compliant to pressure.
True or False. Does a chemical with a LD50 of 1000mg over kg have less toxicity than one with LD50 of 100mg over kg?
True. The chemical with an LD50 of 1000mg/kg is less toxic than the one with an LD50 of 100mg/kg. LD50 is the lethal dose at which 50% of the test subjects die, so the higher the LD50 value, the less toxic the chemical is considered.
How much can you buy Sodium thiopental for?
The price of Sodium thiopental can vary widely depending on factors such as quantity, supplier, and location. It is typically used as an anesthetic and is tightly regulated due to its use in executions, which can affect its availability and price. It is important to ensure that the purchase and use of Sodium thiopental comply with local regulations.
Why do cockroaches survive a nuclear bomb?
The radiation LD50 of most insects is far higher than the LD50 of mammals.
What is the LD50 of methanol for a 100 gram rat?
The LD50 of methanol for rats is typically around 5628 mg/kg. To calculate the LD50 for a 100 gram rat, you would multiply the LD50 value by the weight of the rat in kilograms (100 grams = 0.1 kg) to get an estimated lethal dose.
What is the LD50 standard?
1mg/kg
What is the LD50 value for plutonium?
A probable value for plutonium is LD50 = 5 μg/kg (cumulated chemical and radiological effects).
Why is thiopental much better absorbed from the stomach than barbital when both have similar pKa values?
Thiopental is a weak acid, as is barbital, but it has a higher lipid solubility due to its shorter side chain, facilitating better absorption from the stomach. This increased lipid solubility allows thiopental to cross biological membranes more easily, leading to better absorption compared to barbital despite their similar pKa values.
What is the LD50 of phenobarbital?
The LD50 of phenobarbital in humans is estimated to be around 15 mg/kg when taken orally. LD50 represents the dose at which 50% of the test population would die as a result of the substance.
