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Ceftriaxone is a broad-spectrum cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, disrupting the cross-linking of peptidoglycan, which is essential for maintaining cell wall integrity. This leads to cell lysis and ultimately the death of the bacteria. Ceftriaxone is effective against a wide range of Gram-positive and Gram-negative bacteria.

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