The target cells of calcitriol, the active form of vitamin D, are primarily located in the intestines, kidneys, and bones. In the intestines, it promotes the absorption of calcium and phosphate. In the kidneys, it enhances the reabsorption of calcium, reducing its excretion. In bone, calcitriol regulates the activity of osteoblasts and osteoclasts, influencing bone remodeling and mineralization.
will thyroid produce calcitriol when calcium level is above normal
Perforins are proteins that form pores in the target cell membrane, allowing entry of granzymes into the target cell. Granzymes are enzymes that are delivered into the target cell by perforins and trigger apoptosis, or cell death, in the target cell.
The active form of vitamin D is called calcitriol. It is produced in the kidneys from its precursor, calcidiol, which is formed in the liver. Calcitriol plays a crucial role in regulating calcium and phosphorus levels in the body.
Calcitriol
the endocrine cell has a jelly like substance and so so it drops off it in the blood vessel and so target cells make hormones in the blood vessel to bind into thereceptor on a target cell sometimes a target cell is very close or far away
Vitamin D supplement.
calcitriol, renin, erythropoietin
Cell Wall
Most oral supplements of vitamin D are in the form of ergocalciferol. It is also available in topical (calcitriol or calcipotriene), intravenous (calcitriol), or intramuscular (ergocalciferol) formulations.
Reninerythropoietincalcitroil
Target cell
Corsibula