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The dose of a drug which kills 50 animals was 60mgkg the dose of a drug which cured 50 animals was20mgkg calculate the therapeutic index of the drug?
The therapeutic index of a drug is determined by dividing the lethal dose (LD50) by the effective dose (ED50). In this case: Therapeutic index = LD50/ED50 = 60mg/kg / 20mg/kg = 3. This means that the drug has a therapeutic index of 3, indicating a relatively safe drug with a wide margin of safety.
What is the therapeutic dose for Manic Depression and the use of depakote?
How much you take depends on your weight.
Why should lithium be closely monitored in bipolar disorder?
Often the therapeutic dose is very close to the toxic dose.
What is methadone peak and trough?
Measures the amount of methadone in your system an hour after the last dose and before the next dose. To see if the drug is at a therapeutic level
What is ed50?
The ED50 defined as the dose required to produce a defined therapeutic response in 50% of the population.
Is taking 0.5 mg/L of Alprazolam for Insomnia have a Therapeutic Range when blood was taken 16 hours after the first and only dose is taken at 11 pm every night Is there a therapeutic range for alprazolam for insomnia Doesn't therapeutic mean 'predose'?
The "therapeutic dose" is the dosage that works for that purpose for which is it ordered by a physician. It's not clear what is meant by "blood was taken . . . " Xanax and its generic forms are in the family of benzodiazepines, along with valium and ativan. All benzos are highly addictive and should be used with caution and awareness. While the dose you are describing is not out of line for sleep, it is best to confirm any questions about your medication with your physician.
What is the therapeutic index of drugs?
The therapeutic index of drugs is the ratio between the amount of drug needed to kill 50% of the cells of the experimental animals and the dose needed for 50% of the cells to respond. The larger the therapeutic index, the safer the drug.
What are the nursing responsibilities of digitalis?
Digitalis has a very narrow therapeutic index, therefore, the dose must be carefully be monitored for each patient.
In toxicology reports is 0.07mg of alprazolam lethal?
Considering the fact that 2.0 mg of alprazolam is the highest therapeutic dose, 0.07mg is harmless.
Is therapeutic index a useful measure of safety?
It is for certain drugs such as Digoxin as they have such a narrow therapeutic index. For drugs with a wide range of therapeutic index, the best measure of safety is the maximum daily dose, its effect on the patient and what other drugs it interacts with. Ask your pharmacist for specific safety questions on your specific drugs.
Can aspirin and Prednisone be taken together daily?
Yes you can. Low dose aspirin (82mg) is a sub-therapeutic dose concerning pain and is only effective as a "blood thinner"to prevent blood clots. It is too low of a dose to be of danger to use with oral prednisone.
Is ultram like a Vicodin?
No. Ultram is tramadol HCL. It is a completely different drug that hydrocodone (Vicodin) with a different therapeutic action. Standard dose for standard dose, hydrocodone is somewhat more powerful than tramadol.
