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The therapeutic index is a measure of the safety of a drug, defined as the ratio between the toxic dose and the effective dose. It indicates how much higher the dose needed to produce a toxic effect is compared to the dose that elicits the desired therapeutic effect. A higher therapeutic index suggests a wider margin of safety, while a lower index indicates a greater risk of toxicity. This metric is crucial in pharmacology for determining appropriate dosing regimens.

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2d ago

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