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Innate immunity (also called nonspecific or natural immunity) refers to the inborn ability of the body to resist and is genetically transmitted from one generation to the next. This immunity offers resistance to any microorganism or foreign material encountered by the host.

It includes general mechanisms inherited as part of the innate structure and function of each vertebrate and acts as the first line of defense. Innate immunity lacks immunological memory, i.e., it occurs to the same extent each time a microorganism or foreign material is encountered.

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