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No one has ever died from a cannabis overdose; the therapeutic ratio of THC being around 20000:1 (alcohol 10:1, heroin 6:1). This means that the lethal dose is 20000 times the active dose. One would have to smoke 1500 pounds in 14 minutes to overdose; a feat commonly considered impossible. That being said, the long-term effects of cannabis are a subject of fierce debate. Accidents such as car crashes are possible while under the influence of cannabis, though not common as when one is high they have absolutely no motivation to go drive around.

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