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Suppositories, particularly those containing active pharmaceutical ingredients, can pose serious risks such as rectal irritation, systemic toxicity, or unintentional overdose if not used correctly. Incorrect dosing or inappropriate formulation can lead to adverse effects, especially in vulnerable populations like children or the elderly. Additionally, the risk of infection or injury during insertion is a concern, particularly if proper hygiene is not maintained. It's crucial that suppositories are used according to medical guidance to minimize these risks.

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2w ago

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